Evaluation of Serum Thyroxine Test (T4-RIA)
نویسندگان
چکیده
منابع مشابه
Serum Thyroxine (t4) and Thyroid Stimulating Hormone (tsh) Levels in Cord Blood of Newborns in Lahore
Objective: The primary aim of this study was the early detection and treatment of hypothyroidism in neonates. This paper describes the determination of cord blood serum T4 and TSH levels, their mean levels, reference ranges and interrelationship. Design: Retrospective analysis of serum T4 and TSH levels in 1153 cord blood samples collected and analyzed during July 1998 to June 2000. Setting: Ce...
متن کاملQuantifying spurious free T4 results attributable to thyroxine-binding proteins in serum dialysates and ultrafiltrates.
BACKGROUND Direct equilibrium dialysis and direct ultrafiltration free thyroxine (T(4)) assays rely on semipermeable membranes to exclude T(4)-binding serum proteins from dialysates and ultrafiltrates. The presence of these proteins in dialysates or ultrafiltrates will yield spuriously high free T(4) values when free T(4) is quantified by RIA. METHODS We used a nonanalog free T(4) RIA that de...
متن کاملEvaluation of fluorescence polarization immunoassay for serum thyroxine determination.
We have evaluated a fluorescence polarization immunoassay for thyroxine (T4) using the polarization analyzer IBF-129. Fluorescence polarization could be measured within 20 to 23 seconds after addition of fluorescein labeled thyroxine. The method exhibited excellent specificity and acceptable accuracy. The average intra- and inter-assay coefficients of variation were 4.8 and 12.3%, resepectively...
متن کاملThyroxine-binding by Serum
The occurrence of hypercholesterolemia, lowered basal metabolic rate and depressed serum proteinbound iodine in the nephrotic syndrome has directed attention to the thyroid gland in this disorder. Although hypothyroidism has been suspected, these patients are usually considered, on clinical grounds, to be euthyroid, and they fail to respond in a specific manner to even large doses of thyroid ho...
متن کاملA direct free thyroxine (T4) immunoassay with the characteristics of a total T4 immunoassay.
BACKGROUND Direct free thyroxine (T(4)) measurements have been linked to both T(4)-binding serum protein concentrations and protein-bound T(4) concentrations. Whether this is evidence of a relationship to total T(4) concentrations has not been reported. METHODS We compared an analog-based direct free T(4) immunoassay and a total T(4) immunoassay. Each assay was applied to the fractions of ser...
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1975
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.24.12_885